Dantrolene
نویسندگان
چکیده
منابع مشابه
Dantrolene and lymphocytic lymphoma.
A patient is reported who was on prolonged treatment with dantrolene for spastic paraplegia; he developed a malignant lymphoma which led to his death.
متن کاملHepatitis from dantrolene sodium.
The clinical course and histological changes in the liver during a presumed adverse reaction to the drug dantrolene sodium are described in four patients. After a typical prodrome one developed a moderately severe hepatitis-like illness. Another also had a prodrome but never became jaundiced. In the other two, abnormal liver function tests were detected on routine screening. In each case liver ...
متن کاملDantrolene sodium and management of malignant hyperthermia.
Malignant hyperthermia (MH) is an inherited muscle disorder suffered by patients who undergo a stressful situation or acute trauma or who have been given certain anesthetic agents. 1,2 MH has been called the most common cause of anesthesiarelated death in North America, contributing a large percentage of the 15,000 to 20,000 of such deaths recorded annually.3 The 53% mortality rate of today com...
متن کاملDantrolene requires Mg2+ to arrest malignant hyperthermia.
Malignant hyperthermia (MH) is a clinical syndrome of skeletal muscle that presents as a hypermetabolic response to volatile anesthetic gases, where susceptible persons may develop lethally high body temperatures. Genetic predisposition mainly arises from mutations on the skeletal muscle ryanodine receptor (RyR). Dantrolene is administered to alleviate MH symptoms, but its mechanism of action a...
متن کاملDantrolene for the treatment of MDMA toxicity.
MDMA (3,4-methylenedioxymethamphetamine), popularly known as “Ecstasy,” was first introduced and patented by Merck & Co., Inc., in 1914 as an appetite suppressant. Currently, its primary role is as an illegal stimulant used to produce a euphoric effect during parties. This case report de scribes a 31-year-old man who, after taking 3 tablets of Ecstasy, presented to an emergency department with ...
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ژورنال
عنوان ژورنال: Canadian Anaesthetists’ Society Journal
سال: 1984
ISSN: 0008-2856,1496-8975
DOI: 10.1007/bf03011484